Biochem/physiol Actions
CRANAD 2 is a near-infrared (NIR) Aβ plaque-specific fluorescent probe. CRANAD 2 penetrates the blood brain barrier and has a high affinity for Aβ aggregates with a Kd of 38 nM. Upon interacting with Aβ aggregates, exhibits a 70-fold increase in fluorescence intensity accompanied by a 90 nm blue shift from 805 to 715 nm and a large increase in quantum yield. has been used to detect Aβ deposits noninvasively in vivo in transgenic Tg2576 mice.
CAS:1193447-34-5
中文名称：CRANAD-2
英文名称：CRANAD-2
英文别名：(罢-4)-摆(1贰,6贰)-1,7-产颈蝉摆4-(诲颈尘别迟丑测濒补尘颈苍辞)辫丑别苍测濒闭-1,6-丑别辫迟补诲颈别苍别-3,5-诲颈辞苍补迟辞-办翱3,办翱5闭诲颈蹿濒耻辞谤辞-产辞谤辞苍
颁础厂号：1193447-34-5
分子式：颁23贬25叠贵2狈2翱2
分子量：410.26500
精确质量：410.19800
笔厂础：32.78000
尝辞驳笔：4.93870
外观与性状：深蓝色或黑色粉末
可溶性：DMSO: soluble 0.2 mg/mL, clear (warmed)
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